Illnesses are burdensome or even dramatic events. Living with them and coping is never an easy thing, esp. with chronic progressive illnesses. Mood state problems such as anxieties or depression partly come along with them and with older age in increased intensity.
For the patient, an illness can evolve into an own universe absorbing and shaping the individual as a person, as a patient and their life and depending on severity turn into a life-shaping theme.
But illnesses are not un-dynamic given facts. Along with the changing societies, the cultures and viewpoints of how to handle illnesses, their treatment options are changing and so is the position of the patient within the illness dynamics.